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Data

A database of ancillary volumes is available online, a supplement to the Mouse Atlas Project core volumes. They represent different developmental time points and methods of preparation. To facilitate the process of selecting and analyzing image data from this collection, we have developed a relational database application to manage and catalogue the images and related data. Attributes of the subject such as age, strain, weight and anatomical structure are recorded, as are image volume properties such as modality, resolution and anatomical structure.

These data volumes consist of blockface imaging, classical histology, immunohistochemistry, and in situ hybridization image volumes. They range from a spatial resolution of approximately 100 x 100 x 100 µm3 (128 x 256 x 128 voxels, 4.2 Mb uncompressed) for a low-resolution grayscale MRI volume to 1 x 50 x 1 µm3 (16000 x 16000 x 300 voxels, 180 Gb uncompressed) for a high-resolution full-color Nissl-stained volume.

The Brain Architecture Management System (BAMS; http://brancusi.usc.edu/bkms) is a mature web based knowledge management system that handles data pertaining to four levels of organization of the mammalian central nervous system (CNS): chemical makeup of brain regions, cell types and classes, brain parts, and networks of brain regions. BAMS contains several database modules and web interfaces that make it a unique neuroinformatics resource.

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